& Pre-prints
Uncovering the secret life of Rho GTPases. Perry JA and Maddox AS. eLife. 2019 Dec 13;8. pii: e53276. doi: 10.7554/eLife.53276. PMID: 31833473.
Bond type and discretization of non-muscle myosin II are critical for simulated contractile dynamics D.B. Cortes, M. Gordon, F. Nédélec, A.S. Maddox. BioRxiv
doi: https://doi.org/10.1101/669382
Novel cytokinetic ring components limit RhoA activity and contractility. Kathryn Rehain Bell, Michael E. Werner, Anusha Doshi, Daniel B. Cortes, Adam Sattler, Thanh Vuong-Brender, Michel Labouesse, Amy Shaub Maddox. BioRxiv. doi: https://doi.org/10.1101/633743
Spherical spindle shape promotes perpendicular cortical orientation by preventing isometric cortical pulling on both spindle poles during C. elegans female meiosis.Vargas E, McNally KP, Cortes DB, Panzica MT, Danlasky BM, Li Q, Maddox AS, McNally FJ. Development. 2019 Oct 21;146(20). pii: dev178863. doi: 10.1242/dev.178863. PMID: 31575646
Cell cycle, cell division, cell death. Maddox AS, Skotheim JM. Mol Biol Cell. 2019 Mar 15;30(6):732. doi: 10.1091/mbc.E18-12-0819. PMID: 30870093.
Unite to divide – how models and biological experimentation have come together to reveal mechanisms of cytokinesis. Cortes DB, Dawes A, Liu J, Nickaeen M, Strychalski W, Maddox AS. J Cell Sci. 2018 Dec 18;131(24). pii: jcs203570. doi: 10.1242/jcs.203570. PMID: 30563924
Developmental Diversity in Cell Division Mechanisms. Werner ME, Maddox AS. Dev Cell. 2018 Dec 3;47(5):535-536. doi: 10.1016/j.devcel.2018.11.028. PMID: 30513295
Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing. Lacroix B, Letort G, Pitayu L, Sallé J, Stefanutti M, Maton G, Ladouceur AM, Canman JC, Maddox PS, Maddox AS, Minc N, Nédélec F, Dumont J. Dev Cell. 2018 May 21;45(4):496-511.e6. doi: 10.1016/j.devcel.2018.04.022. PMID: 28285996
Building interdisciplinary bridges to study intercellular bridges. Research Features, Gloucestershire, UK. (click title for free pdf)
LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching. Fadero TC, Gerbich TM, Rana K, Suzuki A, DiSalvo M, Schaefer KN, Heppert JK, Boothby TC, Goldstein B, Peifer M, Allbritton NL, Gladfelter AS, Maddox AS, Maddox PS. J Cell Biol. 2018 May 7;217(5):1869-1882. doi: 10.1083/jcb.201710087. Epub 2018 Feb 28.
Crosslinkers both drive and brake cytoskeletal remodeling and furrowing in cytokinesis. Patino Descovich C*, Cortes DB*, Ryan S, Nash J, Li Z, Maddox PS, Nedelec F, Maddox AS. bioRxiv doi: https://doi.org/10.1101/150813
Variations on a theme: Imaging cytokinetic and stable rings in situ using Caenorhabditis elegans. Rehain K, Green RA, Bourdages KG, Maddox AS. Methods Cell Biol. 2017;137:267-281. doi: 10.1016/bs.mcb.2016.03.039. Epub 2016 May 6.
CENP-A and topoisomerase-II antagonistically affect chromosome length. Ladouceur AM, Ranjan R, Smith L, Fadero T, Heppert J, Goldstein B, Maddox AS, Maddox PS. J Cell Biol. 2017 Jul 21. pii: jcb.201608084. doi: 10.1083/jcb.201608084.
A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges. Rehain-Bell K, Love A, Werner ME, MacLeod I, Yates JR 3rd, Maddox AS. Curr Biol. 2017 Mar 20;27(6):860-867. doi: 10.1016/j.cub.2017.01.058. Epub 2017 Mar 9. PMID: 28285996
Identification of microtubule growth deceleration and its regulation by conserved and novel proteins. Lacroix B, Ryan J, Dumont J, Maddox PS, Maddox AS. Mol Biol Cell. 2016 Mar 16. pii: mbc.E16-01-0056. PMID: 26985017
A theoretical model of cytokinesis implicates feedback between membrane curvature and cytoskeletal organization in asymmetric cytokinetic furrowing. Dorn JF, Zhang L, Phi TT, Lacroix B, Maddox PS, Liu J, Maddox AS. Mol Biol Cell. 2016 Feb 24. pii: mbc.E15-06-0374. PMID: 26912796
Neuron migration: anillin protects leading edge actin. Rehain K, Maddox AS. Curr Biol. 2015 18;25(10):R423-5. doi: 10.1016/j.cub.2015.03.030. PMID: 25989084
Anillin localization suggests distinct mechanisms of division plane specification in mouse oogenic meiosis I and II. Sharif B, Fadero T, Maddox AS. Gene Expr Patterns. 2015 Mar 26;17(2):98-106. PMID: 25818309
Quantitative analysis of cytokinesis in situ during C. elegans postembryonic development. Bourdages KG, Lacroix B, Dorn JF, Descovich CP, Maddox AS. PLoS One. 2014 Oct 20;9(10):e110689. PMID: 25329167
Celegans Anillin proteins regulate intercellular bridge stability and germline syncytial organization. Amini R, Goupil E, Labella S, Zetka M, Maddox AS, Labbé JC, Chartier NT. J Cell Biol. 2014 Jul 7;206(1):129-43. PMID: 24982432
In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics. Lacroix B, Bourdages KG, Dorn JF, Ihara S, Sherwood DR, Maddox PS, Maddox AS. Dev Cell. 2014 Apr 28;29(2):203-16. PMID: 24780738
Dividing in epithelia: cells let loose during cytokinesis. Bourdages KG, Maddox AS. Dev Cell. 2013 Feb 25;24(4):336-8. Erratum in: Dev Cell. 2013 Mar 25;24(6):668. PMID: 23449467
Polar body cytokinesis. Maddox AS, Azoury J, Dumont J. Cytoskeleton (Hoboken). 2012 Nov;69(11):855-68. PMID: 22927361
Wound healing: GTPases flux their muscles. Sharif B, Maddox AS. Dev Cell. 2012 Aug 14;23(2):236-8. PMID: 22898773
Imaging the mitotic spindle. Maddox PS, Ladouceur AM, Ranjan R, Dorn J, Ratsima H, D’Amours D, Maddox AS. Methods Enzymol. 2012;505:81-103. PMID: 22289449
High-resolution imaging of cellular processes in Caenorhabditis elegans. Maddox AS, Maddox PS. Methods Cell Biol. 2012;107:1-34. PMID: 22226519
Cytokinesis: cells go back and forth about division. Dorn JF, Maddox AS. Curr Biol. 2011 Oct 25;21(20):R848-50. PMID: 22032188
Cytokinesis, ploidy and aneuploidy. Lacroix B, Maddox AS. J Pathol. 2012 Jan;226(2):338-51. PMID: 21984283
The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. Lewellyn L, Carvalho A, Desai A, Maddox AS, Oegema K. J Cell Biol. 2011 Apr 4;193(1):155-69. PMID: 21464231
PAR-4/LKB1 mobilizes nonmuscle myosin through anillin to regulate C. elegans embryonic polarization and cytokinesis. Chartier NT, Salazar Ospina DP, Benkemoun L, Mayer M, Grill SW, Maddox AS, Labbé JC. Curr Biol. 2011 Feb 22;21(4):259-69. PMID: 21276723
A small GTPase molecular switch regulates epigenetic centromere maintenance by stabilizing newly incorporated CENP-A. Lagana A, Dorn JF, De Rop V, Ladouceur AM, Maddox AS, Maddox PS. Nat Cell Biol. 2010 Dec;12(12):1186-93. PMID: 21102442
Actomyosin tube formation in polar body cytokinesis requires Anillin in C. elegans. Dorn JF, Zhang L, Paradis V, Edoh-Bedi D, Jusu S, Maddox PS, Maddox AS. Curr Biol. 2010 Nov 23;20(22):2046-51. PMID: 21055941
The myriad roles of Anillin during cytokinesis. Piekny AJ, Maddox AS. Semin Cell Dev Biol. 2010 Dec;21(9):881-91. PMID: 20732437
Quick guide: Anillin. Zhang L, Maddox AS. Curr Biol. 2010 Feb 23;20(4):R135-6. PMID: 20178751
Anillin and the septins promote asymmetric ingression of the cytokinetic furrow. Maddox AS, Lewellyn L, Desai A, Oegema K. Dev Cell. 2007 May;12(5):827-35. PMID: 17488632
A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. Audhya A, Hyndman F, McLeod IX, Maddox AS, Yates JR 3rd, Desai A, Oegema K. J Cell Biol. 2005 Oct 24;171(2):267-79. PMID: 16247027
Distinct roles for two C. elegans anillins in the gonad and early embryo. Maddox AS, Habermann B, Desai A, Oegema K. Development. 2005 Jun;132(12):2837-48. PMID: 15930113
Simultaneous stretching and contraction of stress fibers in vivo. Peterson LJ, Rajfur Z, Maddox AS, Freel CD, Chen Y, Edlund M, Otey C, Burridge K. Mol Biol Cell. 2004 Jul;15(7):3497-508. PMID: 15133124
Deconstructing cytokinesis. Maddox AS, Oegema K. Nat Cell Biol. 2003 Sep;5(9):773-6. Review. PMID: 12951607
Closing the GAP: a role for a RhoA GAP in cytokinesis. Maddox AS, Oegema K. Mol Cell. 2003 Apr;11(4):846-8. Review. PMID: 12718869
RhoA is required for cortical retraction and rigidity during mitotic cell rounding. Maddox AS, Burridge K. J Cell Biol. 2003 Jan 20;160(2):255-65. PMID: 12538643
Understanding Ras: ‘it ain’t over ’til it’s over’. Shields JM, Pruitt K, McFall A, Shaub A, Der CJ. Trends Cell Biol. 2000 Apr;10(4):147-54. Review. PMID: 10740269
Unravelling the extracellular matrix. Shaub A. Nat Cell Biol. 1999 Nov;1(7):E173-5. No abstract available. PMID: 10559994
Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly. Zhong C, Chrzanowska-Wodnicka M, Brown J, Shaub A, Belkin AM, Burridge K. J Cell Biol. 1998 Apr 20;141(2):539-51. PMID: 9548730
Relationship of Methyl Transferase Activity and Methyl Farnesoate Levels in the Spider Crab, Libinia emarginata J. Ogan, A. Shaub, D. L. Lovett, and D. W. Borst Biol Bull 1997 193:267-268.